Any avid bettor will tell you that knowing the odds is a crucial part of making an informed bet. That is not to say you have to bet in accordance with the odds, but being aware of how bookies and oddsmakers view sporting contests can be an indicator of what to expect.
This page includes information regarding the odds for this year’s NFL and NCAA Thanksgiving football games. There are some clear favorites and some games that are considered to be closer. In any case, use these odds as a resource in helping you determine which team(s) you want to bet on.
2022 NFL Thanksgiving Odds
There are three NFL games slated for Thanksgiving Day, with the nightly Buffalo Bills at Detroit Lions starting around the time most people will be getting their first helping of turkey.
The second game is an NFC East clash featuring the New York Giants at the Dallas Cowboys, which will immediately follow the Detroit Lions game.
Finally, everyone will be in for a treat as the New England Patriots travel to face the Minnesota Vikings in primetime. We update the odds below once they are made available.
To check the odds in real time, you can go here. You may also want to check out our NFL Thanksgiving betting page, which offers information specific to betting on these NFL Thanksgiving games. We also have in-depth previews of the games to help you gain some insight for your betting strategy.
NFL Betting Odds For Thanksgiving 2022
| Matchup | Moneyline | Spread | Over/Under |
|---|---|---|---|
 | Bills: -450 Lions: +335 | Bills: -9.0 Lions: +9.0 | Bills: O 53.5 Lions: U 53.5 |
 | Cowboys: -315 Giants: +420 | Cowboys: -9.0 Giants: +9.0 | Cowboys: U 44.5 Giants: O 44.5 |
 | Patriots: +130 Vikings: -150 | Patriots: +3.0 Vikings: -3.0 | Patriots: O 42.0 Vikings: U 42.0 |
Where To Bet On Thanksgiving Football
| Sportsbook | Current Bonus | U.S. | Link |
|---|---|---|---|
 | 50% bonus up to $250 |  | Visit Site |
 | 50% bonus up to $1,000 | | Visit Site |
 | 50% bonus up to $1,000 | | Visit Site |
 | 50% bonus up to $1,000 | | Visit Site |
2022 NCAAF Thanksgiving Odds
The NCAA has a lot of games set for Thanksgiving weekend, but the only college football game that is scheduled for the actual holiday is Ole Miss vs. Mississippi State. Check out our Thanksgiving college football page for in-depth previews and schedules for the NCAAF games occurring over the holiday weekend.
Ole Miss Rebels vs. Mississippi State Bulldogs
- Thursday, November 24 at 7:30 pm
- Point Spread: MSU +2.5, MISS -2.5
- Moneyline Odds To Win: MSU +110, MISS -130
- Over/Under: 59.0
About Football Betting Lines And Odds
Football is the most popular sport in the US. The level of engagement with fans and the league is evidenced through game attendance, fan energy, and even the popular fantasy football leagues.
While the NFL is everchanging there are things that have turned into a tradition over time, including the Detroit Lions Thanksgiving game and the Dallas Cowboys Thanksgiving game.
Fans love to pit their football intelligence against each other, and betting on the NFL during Thanksgiving allows those competitive fans to put their money where their mouth is, and the section below explains just how many ways you can do that.
Types Of Bets For Thanksgiving Day Football Games
Point Spread
The most common way of betting on Thanksgiving football games is with the point spread. The point spread is a predetermined point differential set by oddsmakers to make an “even” matchup by taking points away from the favorite and giving them to the underdog.
Moneyline
Moneyline bets involve betting on a team to win the game outright with no points given. The favorite is given a lower payout for winning, but the underdog gets a higher payout should the team pull off the upset.
Over/Under Total
Over/Under total bets involve betting on the combined number of points from the final score of the game with a bet needing to be placed on whether total points will fall above or below a set number.
Prop Bets
Prop bets are based on occurrences or non-occurrences throughout the broadcast but may or may not affect the final outcome of the game.
Futures
These are wagers placed weeks or months in advance where the odds of winning are more uncertain, which increases the payout if the bet is won.
Parlays
Parlay betting raises the stakes by combining multiple bets into one by betting on a series of outcomes to increase the payout while increasing risk since any bet lost means losing the entire parlay.